The Toll-like receptor 4 agonist MRP8/14 protein complex is a sensitive indicator for disease activity and predicts relapses in systemic-onset juvenile idiopathic arthritis.

Holzinger D, Frosch M, Kastrup A, Prince FH, Otten MH, Van Suijlekom-Smit LW, ten Cate R, Hoppenreijs EP, Hansmann S, Moncrieffe H, Ursu S, Wedderburn LR, Roth J, Foell D, Wittkowski H (2012)
In: Annals of the Rheumatic Diseases, 71(6)
Art der Publikation: Forschungsartikel (Zeitschrift)

H5N1 virus activates signaling pathways in human endothelial cells resulting in a specific imbalanced inflammatory response.

Viemann D, Schmolke M, Lueken A, Boergeling Y, Friesenhagen J, Wittkowski H, Ludwig S, Roth J (2011)
In: The Journal of Immunology, 186(1)
Art der Publikation: Forschungsartikel (Zeitschrift)

MRP8 and MRP14, phagocyte-specific danger signals, are sensitive biomarkers of disease activity in cryopyrin-associated periodic syndromes.

Wittkowski H, Kuemmerle-Deschner JB, Austermann J, Holzinger D, Goldbach-Mansky R, Gramlich K, Lohse P, Jung T, Roth J, Benseler SM, Foell D (2011)
In: Annals of the Rheumatic Diseases, 70(12)
Art der Publikation: Forschungsartikel (Zeitschrift)

Towards a risk-adapted maintenance therapy in remission of juvenile idiopathic arthritis: A randomized trial on 6 vs. 12 months withdrawal of methotrexate

Foell D, Wittkowski H, Frosch M, Roth J (2010)
In: European Journal of Pediatrics, 169(3)
Art der Publikation: Forschungsartikel (Zeitschrift)

Methotrexate withdrawal at 6 vs 12 months in juvenile idiopathic arthritis in remission: a randomized clinical trial.

Foell D, Wulffraat N, Wedderburn LR, Wittkowski H, Frosch M, Gerss J, Stanevicha V, Mihaylova D, Ferriani V, Tsakalidou FK, Foeldvari I, Cuttica R, Gonzalez B, Ravelli A, Khubchandani R, Oliveira S, Armbrust W, Garay S, Vojinovic J, Norambuena X, Gamir ML, García-Consuegra J, Lepore L, Susic G, Corona F, Dolezalova P, Pistorio A, Martini A, Ruperto N, Roth J, Paediatric Rheumatology International Trials Organization (PRINTO) (2010)
In: Journal of the American Medical Association, 303(13)
Art der Publikation: Forschungsartikel (Zeitschrift)

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A child with soft-tissue infection and lymphadenitis Froböse NJ, Masjosthusmann K, Huss S, Correa-Martinez CL, Mellmann A, Schuler F, Kahl BC, Wittkowski H, Schaumburg F (2020) In: New Microbes New Infect, 38 Art der Publikation: Forschungsartikel (Zeitschrift)
The Toll-like receptor 4 agonist MRP8/14 protein complex is a sensitive indicator for disease activity and predicts relapses in systemic-onset juvenile idiopathic arthritis. Holzinger D, Frosch M, Kastrup A, Prince FH, Otten MH, Van Suijlekom-Smit LW, ten Cate R, Hoppenreijs EP, Hansmann S, Moncrieffe H, Ursu S, Wedderburn LR, Roth J, Foell D, Wittkowski H (2012) In: Annals of the Rheumatic Diseases, 71(6) Art der Publikation: Forschungsartikel (Zeitschrift)
Efficacy and safety of anakinra therapy in pediatric and adult patients with the autoinflammatory Muckle-Wells syndrome. Kuemmerle-Deschner JB, Tyrrell PN, Koetter I, Wittowski H, Bialkowski A, Tzaribachev N, Lohse P, Koitchev A, Deuter C, Foell D, Benseler SM (2011) In: Arthritis and Rheumatism Art der Publikation: Forschungsartikel (Zeitschrift)
H5N1 virus activates signaling pathways in human endothelial cells resulting in a specific imbalanced inflammatory response. Viemann D, Schmolke M, Lueken A, Boergeling Y, Friesenhagen J, Wittkowski H, Ludwig S, Roth J (2011) In: The Journal of Immunology, 186(1) Art der Publikation: Forschungsartikel (Zeitschrift)
Translational research network and patient registry for auto-inflammatory diseases. Lainka E, Bielak M, Hilger V, Basu O, Neudorf U, Wittkowski H, Holzinger D, Roth J, Niehues T, Foell D (2011) In: Rheumatology, 50(1) Art der Publikation: Forschungsartikel (Zeitschrift)
MRP8 and MRP14, phagocyte-specific danger signals, are sensitive biomarkers of disease activity in cryopyrin-associated periodic syndromes. Wittkowski H, Kuemmerle-Deschner JB, Austermann J, Holzinger D, Goldbach-Mansky R, Gramlich K, Lohse P, Jung T, Roth J, Benseler SM, Foell D (2011) In: Annals of the Rheumatic Diseases, 70(12) Art der Publikation: Forschungsartikel (Zeitschrift)
New genetic variations in the PSTPIP1 gene leading to auto-inflammation distinct from classical PAPA syndrome Holzinger D, Lohse P, Fessatou S, Isidor B, Knudsen PK, Sampson B, Koichi I, Ehrchen J, Wittkowski H, Sunderkoetter C, Roth J (2011) In: Clinical and Experimental Rheumatology, 29(2) Art der Publikation: Forschungsartikel (Zeitschrift)
Towards a risk-adapted maintenance therapy in remission of juvenile idiopathic arthritis: A randomized trial on 6 vs. 12 months withdrawal of methotrexate Foell D, Wittkowski H, Frosch M, Roth J (2010) In: European Journal of Pediatrics, 169(3) Art der Publikation: Forschungsartikel (Zeitschrift)
Neutrophil-derived S100A12 as novel biomarker of inflammation in familial Mediterranean fever. Kallinich T, Wittkowski H, Keitzer R, Roth J, Foell D (2010) In: Annals of the Rheumatic Diseases, 69(4) Art der Publikation: Forschungsartikel (Zeitschrift)
Methotrexate withdrawal at 6 vs 12 months in juvenile idiopathic arthritis in remission: a randomized clinical trial. Foell D, Wulffraat N, Wedderburn LR, Wittkowski H, Frosch M, Gerss J, Stanevicha V, Mihaylova D, Ferriani V, Tsakalidou FK, Foeldvari I, Cuttica R, Gonzalez B, Ravelli A, Khubchandani R, Oliveira S, Armbrust W, Garay S, Vojinovic J, Norambuena X, Gamir ML, García-Consuegra J, Lepore L, Susic G, Corona F, Dolezalova P, Pistorio A, Martini A, Ruperto N, Roth J, Paediatric Rheumatology International Trials Organization (PRINTO) (2010) In: Journal of the American Medical Association, 303(13) Art der Publikation: Forschungsartikel (Zeitschrift)