The second PI(3,5)P2 binding site in the S0 helix of KCNQ1 stabilizes PIP2-at the primary PI1 site with potential consequences on intermediate-to-open state transition.

Dellin, Maurice; Rohrbeck, Ina; Asrani, Purva; Schreiber, Julian A; Ritter, Nadine; Glorius, Frank; Wünsch, Bernhard; Budde, Thomas; Temme, Louisa; Strünker, Timo; Stallmeyer, Birgit; Tüttelmann, Frank; Meuth, Sven G; Spehr, Marc; Matschke, Johann; Steinbicker, Andrea; Gatsogiannis, Christos; Stoll, Raphael; Strutz-Seebohm, Nathalie; Seebohm, Guiscard (2023)

In: Journal of Biological Chemistry, 404(4).

Forschungsartikel (Zeitschrift)

Chemical, pharmacodynamic and pharmacokinetic characterization of the GluN2B receptor antagonist 3-(4-phenylbutyl)-2,3,4,5-tetrahydro-1H-3-benzazepine-1,7-diol - starting point for PET tracer development.

Korff M; Steigerwald R; Bechthold E; Schepmann D; Schreiber JA; Meuth SG; Seebohm G; Wünsch B (2023)

In: Biological Chemistry, 404(4).

Forschungsartikel (Zeitschrift)

The second PI(3,5)P2 binding site in the S0 helix of KCNQ1 stabilizes PIP2-at the primary PI1 site with potential consequences on intermediate-to-open state transition.

Dellin M; Rohrbeck I; Asrani P; Schreiber JA; Ritter N; Glorius F; Wünsch B; Budde T; Temme L; Strünker T; Stallmeyer B; Tüttelmann F; Meuth SG; Spehr M; Matschke J; Steinbicker A; Gatsogiannis C; Stoll R; Strutz-Seebohm N; Seebohm G (2023)

In: Biological Chemistry, 404(4).

Forschungsartikel (Zeitschrift)

A benzodiazepine activator locks Kv7.1 channels open by electro-mechanical uncoupling.

Schreiber JA; Möller M; Zaydman M; Zhao L; Beller Z; Becker S; Ritter N; Hou P; Shi J; Silva J; Wrobel E; Strutz-Seebohm N; Decher N; Schmitt N; Meuth SG; Düfer M; Wünsch B; Cui J; Seebohm G (2022)

In: Communications biology, 5(1).

Forschungsartikel (Zeitschrift)

A common mechanism allows selective targeting of GluN2B subunit-containing N-methyl-D-aspartate receptors

Schreiber, Julian A.; Schepmann, Dirk; Frehland, Bastian; Thum, Simone; Datunashvili, Maia; Budde, Thomas; Hollmann, Michael; Strutz-Seebohm, Nathalie; Wünsch, Bernhard; Seebohm, Guiscard (2019)

In: Communications biology, 2, 420.

Forschungsartikel (Zeitschrift)

The ubiquitination landscape of the influenza A virus polymerase Günl F.; Krischuns T.; Schreiber J.A.; Henschel L.; Wahrenburg M.; Drexler H.C.A.; Leidel S.A.; Cojocaru V.; Seebohm G.; Mellmann A.; Schwemmle M.; Ludwig S.; Brunotte L.; (2023) In: Nature Communications, 14(1). Forschungsartikel (Zeitschrift)
The second PI(3,5)P2 binding site in the S0 helix of KCNQ1 stabilizes PIP2-at the primary PI1 site with potential consequences on intermediate-to-open state transition. Dellin, Maurice; Rohrbeck, Ina; Asrani, Purva; Schreiber, Julian A; Ritter, Nadine; Glorius, Frank; Wünsch, Bernhard; Budde, Thomas; Temme, Louisa; Strünker, Timo; Stallmeyer, Birgit; Tüttelmann, Frank; Meuth, Sven G; Spehr, Marc; Matschke, Johann; Steinbicker, Andrea; Gatsogiannis, Christos; Stoll, Raphael; Strutz-Seebohm, Nathalie; Seebohm, Guiscard (2023) In: Journal of Biological Chemistry, 404(4). Forschungsartikel (Zeitschrift)
Downstream Allosteric Modulation of NMDA Receptors by 3-Benzazepine Derivatives Ritter N; Disse P; Aymanns I; Mücher L; Schreiber JA; Brenker C; Strünker T; Schepmann D; Budde T; Strutz-Seebohm N; Ametamey SM; Wünsch B; Seebohm G (2023) In: Molecular Neurobiology, 60(12). Forschungsartikel (Zeitschrift)
Chemical, pharmacodynamic and pharmacokinetic characterization of the GluN2B receptor antagonist 3-(4-phenylbutyl)-2,3,4,5-tetrahydro-1<i>H</i>-3-benzazepine-1,7-diol - starting point for PET tracer development. Korff M; Steigerwald R; Bechthold E; Schepmann D; Schreiber JA; Meuth SG; Seebohm G; Wünsch B (2023) In: Biological Chemistry, 404(4). Forschungsartikel (Zeitschrift)
Cloxyquin activates hTRESK by allosteric modulation of the selectivity filter. Schreiber JA; Derksen A; Goerges G; Schütte S; Sörgel J; Kiper AK; Strutz-Seebohm N; Ruck T; Meuth SG; Decher N; Seebohm G (2023) In: Communications biology, 6(1). Forschungsartikel (Zeitschrift)
The second PI(3,5)P2 binding site in the <i>S0</i> helix of KCNQ1 stabilizes PIP2-at the primary <i>PI1</i> site with potential consequences on intermediate-to-open state transition. Dellin M; Rohrbeck I; Asrani P; Schreiber JA; Ritter N; Glorius F; Wünsch B; Budde T; Temme L; Strünker T; Stallmeyer B; Tüttelmann F; Meuth SG; Spehr M; Matschke J; Steinbicker A; Gatsogiannis C; Stoll R; Strutz-Seebohm N; Seebohm G (2023) In: Biological Chemistry, 404(4). Forschungsartikel (Zeitschrift)
Effects of Axonal Demyelination, Inflammatory Cytokines and Divalent Cation Chelators on Thalamic HCN Channels and Oscillatory Bursting Oniani T, Vinnenberg L, Chaudhary R, Schreiber JA, Riske K, Williams B, Pape HC, White JA, Junker A, Seebohm G, Meuth SG, Hundehege P, Budde T, Zobeiri M (2022) In: International Journal of Molecular Sciences, 23(11), 6285. Forschungsartikel (Zeitschrift)
A benzodiazepine activator locks Kv7.1 channels open by electro-mechanical uncoupling. Schreiber JA; Möller M; Zaydman M; Zhao L; Beller Z; Becker S; Ritter N; Hou P; Shi J; Silva J; Wrobel E; Strutz-Seebohm N; Decher N; Schmitt N; Meuth SG; Düfer M; Wünsch B; Cui J; Seebohm G (2022) In: Communications biology, 5(1). Forschungsartikel (Zeitschrift)
4,4'-Diisothiocyanato-2,2'-Stilbenedisulfonic Acid (DIDS) Modulates the Activity of KCNQ1/KCNE1 Channels by an Interaction with the Central Pore Region Bollmann, Eva; Schreiber, Julian Alexander; Ritter, Nadine; Peischard, Stefan; Ho, Huyen Tran; Wünsch, Bernhard; Strünker, Timo; Meuth, Sven; Budde, Thomas; Strutz-Seebohm, Nathalie; Seebohm, Guiscard (2020) In: Cellular physiology and biochemistry, 54(2). Forschungsartikel (Zeitschrift)
A common mechanism allows selective targeting of GluN2B subunit-containing N-methyl-D-aspartate receptors Schreiber, Julian A.; Schepmann, Dirk; Frehland, Bastian; Thum, Simone; Datunashvili, Maia; Budde, Thomas; Hollmann, Michael; Strutz-Seebohm, Nathalie; Wünsch, Bernhard; Seebohm, Guiscard (2019) In: Communications biology, 2, 420. Forschungsartikel (Zeitschrift)

Publikationen

Betrieben von

Top-Links