Hydrolysis of chitin and chitosans by the human chitinolytic enzymes: chitotriosidase, acidic mammalian chitinase, and lysozyme

Hellmann, Margareta J.; Marongiu, Gian Luca; Gorzelanny, Christian; Moerschbacher, Bruno M.; Cord-Landwehr, Stefan (2025)
In: International Journal of Biological Macromolecules, 297(139789)
Art der Publikation: Forschungsartikel (Zeitschrift)

Transkingdom mechanism of MAMP generation by chitotriosidase feeds oligomeric chitin from fungal pathogens and allergens into TLR2-mediated innate immune sensing

Chang, Tzu-Hsuan; Cardona Gloria, Yamel; Hellmann, Margareta J.; Richardo, Timmy; Greve, Carsten Leo; Le Roy, Didier; Roger, Thierry; Bork, Francesca; Bugl, Stefanie; Jakob, Johanna; Sonnberger, Johannes; Kasper, Lydia; Hube, Bernhard; Pusch, Stefan; Gow, Neil A. R.; Sørlie, Morten; Tøndervik, Anne; Moerschbacher, Bruno M.; Weber, Alexander N. R. (2025)
In: (kein Journal angegeben), 16(1497174)
Art der Publikation: Forschungsartikel (Zeitschrift)

Fast insights into chitosan-cleaving enzymes by simultaneous analysis of polymers and oligomers through size exclusion chromatography

Hellmann, Margareta J.; Moerschbacher, Bruno M.; Cord-Landwehr, Stefan (2024)
In: Scientific Reports, 14
Art der Publikation: Forschungsartikel (Zeitschrift)

Transcriptomics reveal a mechanism of niche defense: two beneficial root endophytes deploy an antimicrobial GH18-CBM5 chitinase to protect their hosts

Eichfeld, Ruben; Mahdi, Lisa K.; De Quattro, Concetta; Armbruster, Laura; Endeshaw, Asmamaw B.; Miyauchi, Shingo; Hellmann, Margareta J.; Cord‐Landwehr, Stefan; Peterson, Daniel; Singan, Vasanth; Lail, Kathleen; Savage, Emily; Ng, Vivian; Grigoriev, Igor V.; Langen, Gregor; Moerschbacher, Bruno M.; Zuccaro, Alga (2024)
In: New Phytologist, 244
Art der Publikation: Forschungsartikel (Zeitschrift)

Engineering of a chitin deacetylase to generate tailor-made chitosan polymers

Bonin, Martin; Irion, Antonia L.; Jürß, Anika; Pascual, Sergi, Cord-Landwehr, Stefan; Planas, Antoni; Moerschbacher, Bruno M. (2023)
In: PLoS Biology, 22(1)
Art der Publikation: Forschungsartikel (Zeitschrift)

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Three intertwining effects guide the mode of action of chitin deacetylase de- and N-acetylation reactions Lindner, Sandra; Bonin, Martin; Hellmann, Margareta J.; Moerschbacher, Bruno M. (2025) In: Carbohydrate Polymers, 347(122725) Art der Publikation: Übersichtsartikel (Zeitschrift)
Hydrolysis of chitin and chitosans by the human chitinolytic enzymes: chitotriosidase, acidic mammalian chitinase, and lysozyme Hellmann, Margareta J.; Marongiu, Gian Luca; Gorzelanny, Christian; Moerschbacher, Bruno M.; Cord-Landwehr, Stefan (2025) In: International Journal of Biological Macromolecules, 297(139789) Art der Publikation: Forschungsartikel (Zeitschrift)
LCP simulator: An easy-to-use web tool to simulate pattern analysis and enzymatic cleavage of binary linear copolymers Hellmann, Margareta J.; Moerschbacher, Bruno M.; Cord-Landwehr, Stefan (2025) In: SoftwareX, 29(102050) Art der Publikation: Forschungsartikel (Zeitschrift)
Transkingdom mechanism of MAMP generation by chitotriosidase feeds oligomeric chitin from fungal pathogens and allergens into TLR2-mediated innate immune sensing Chang, Tzu-Hsuan; Cardona Gloria, Yamel; Hellmann, Margareta J.; Richardo, Timmy; Greve, Carsten Leo; Le Roy, Didier; Roger, Thierry; Bork, Francesca; Bugl, Stefanie; Jakob, Johanna; Sonnberger, Johannes; Kasper, Lydia; Hube, Bernhard; Pusch, Stefan; Gow, Neil A. R.; Sørlie, Morten; Tøndervik, Anne; Moerschbacher, Bruno M.; Weber, Alexander N. R. (2025) In: (kein Journal angegeben), 16(1497174) Art der Publikation: Forschungsartikel (Zeitschrift)
Degree of acetylation of chitosans determined by size exclusion chromatography coupled to UV and refractive index detection Cord-Landwehr, Stefan; Hellmann, Margareta J.; Moerschbacher, Bruno M. (2025) In: Carbohydrate Polymers, 369(June) Art der Publikation: Forschungsartikel (Zeitschrift)
Fast insights into chitosan-cleaving enzymes by simultaneous analysis of polymers and oligomers through size exclusion chromatography Hellmann, Margareta J.; Moerschbacher, Bruno M.; Cord-Landwehr, Stefan (2024) In: Scientific Reports, 14 Art der Publikation: Forschungsartikel (Zeitschrift)
Heterogeneously deacetylated chitosans possess an unexpected regular pattern favoring acetylation at every third position Hellmann, Margareta J.; Gillet, Dominique; Trombotto, Stéphane; Raetz, Sonja; Moerschbacher, Bruno Maria; Cord-Landwehr, Stefan (2024) In: (kein Journal angegeben), 15 Art der Publikation: Forschungsartikel (Zeitschrift)
Transcriptomics reveal a mechanism of niche defense: two beneficial root endophytes deploy an antimicrobial GH18-CBM5 chitinase to protect their hosts Eichfeld, Ruben; Mahdi, Lisa K.; De Quattro, Concetta; Armbruster, Laura; Endeshaw, Asmamaw B.; Miyauchi, Shingo; Hellmann, Margareta J.; Cord‐Landwehr, Stefan; Peterson, Daniel; Singan, Vasanth; Lail, Kathleen; Savage, Emily; Ng, Vivian; Grigoriev, Igor V.; Langen, Gregor; Moerschbacher, Bruno M.; Zuccaro, Alga (2024) In: New Phytologist, 244 Art der Publikation: Forschungsartikel (Zeitschrift)
Chitins and chitosans - A tale of discovery and disguise, of attachment and attainment Student, Mounashree; Hellmann, Margareta J.; Cord-Landwehr, Stefan; Moerschbacher, Bruno M. (2024) In: Current Opinion in Plant Biology, 82(102661) Art der Publikation: Übersichtsartikel (Zeitschrift)
Engineering of a chitin deacetylase to generate tailor-made chitosan polymers Bonin, Martin; Irion, Antonia L.; Jürß, Anika; Pascual, Sergi, Cord-Landwehr, Stefan; Planas, Antoni; Moerschbacher, Bruno M. (2023) In: PLoS Biology, 22(1) Art der Publikation: Forschungsartikel (Zeitschrift)