The host-targeted antiviral drug Zapnometinib exhibits a high barrier to the development of SARS-CoV-2 resistance.

Schreiber A; Rodner F; Oberberg N; Anhlan D; Bletz S; Mellmann A; Planz O; Ludwig S (2024)
In: Antiviral Research, 225
Art der Publikation: Forschungsartikel (Zeitschrift)

Inhibition of p38 signaling curtails the SARS-CoV-2 induced inflammatory response but retains the IFN-dependent antiviral defense of the lung epithelial barrier.

Faist A; Schloer S; Mecate-Zambrano A; Janowski J; Schreiber A; Boergeling Y; Conrad BCG; Kumar S; Toebben L; Schughart K; Baumgardt M; Kessler M; Hoenzke K; Hocke A; Trautmann M; Kato H; Hartmann W; Christersson A; Rescher U; Mellmann A; Kuehn J; Kuempers P; Wolff T; Wiewrodt R; Rovas A; Barth P; Wiebe K; Brunotte L; Ludwig S (2023)
In: Antiviral Research, 209
Art der Publikation: Forschungsartikel (Zeitschrift)

Cell-intrinsic genomic reassortment of pandemic H1N1 2009 and Eurasian avian-like swine influenza viruses results in potentially zoonotic variants.

Ferrando VA; Friedrich ME; Gandhi S; Mellmann A; Masemann D; Christersson A; Anhlan D; Brunotte L; Stoll M; Harder T; Beer M; Boergeling Y; Ludwig S (2023)
In: Emerging Microbes and Infections, 12(1)
Art der Publikation: Forschungsartikel (Zeitschrift)

Surrogate Virus Neutralisation Test Based on Nanoluciferase-Tagged Antigens to Quantify Inhibitory Antibodies against SARS-CoV-2 and Characterise Omicron-Specific Reactivity in a…

Schoefbaenker, M; Neddermeyer, R; Guenther, T; Mueller, MM; Romberg, ML; Classen, N; Hennies, MT; Hrincius, ER; Ludwig, S; Kuehn, JE; Lorentzen, EU (2023)
In: Vaccines, 2023(11)
Art der Publikation: Forschungsartikel (Zeitschrift)

Small spleen peptides prevent development of psoriatic arthritis via restoration of peripheral tolerance

Wixler, V; Zaytsev, IZ; Leite Dantas, R; Schied, T; Boergeling, Y; Lührmann, V; Varga, G; Masemann, D; Ludwig, S (2022)
In: Molecular Therapy, 30(2)
Art der Publikation: Forschungsartikel (Zeitschrift)

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Small Spleen Peptides (SSPs) Shape Dendritic Cell Differentiation through Modulation of Extracellular ATP Synthesis Profile Wixler, Viktor; Leite Dantas, Rafael; Varga, Georg; Boergeling, Yvonne; Ludwig, Stephan (2024) In: Biomolecules, 14(4) Art der Publikation: Forschungsartikel (Zeitschrift)
The host-targeted antiviral drug Zapnometinib exhibits a high barrier to the development of SARS-CoV-2 resistance. Schreiber A; Rodner F; Oberberg N; Anhlan D; Bletz S; Mellmann A; Planz O; Ludwig S (2024) In: Antiviral Research, 225 Art der Publikation: Forschungsartikel (Zeitschrift)
Characterisation of the antibody-mediated selective pressure driving intra-host evolution of SARS-CoV-2 in prolonged infection Schoefbaenker, M; Günther, T; Lorentzen, EU; Romberg, M-L; Hennies, MT; Neddermeyer, R; Müller, MM; Mellmann, A; Bojarzyn, CR; Lenz, G; Stelljes, M; Hrincius, ER; Vollenberg, R; Ludwig, S; Tepasse, P-R; Kühn, JE (2024) In: PLoS Pathogens, 20(10) Art der Publikation: Forschungsartikel (Zeitschrift)
Inhibition of p38 signaling curtails the SARS-CoV-2 induced inflammatory response but retains the IFN-dependent antiviral defense of the lung epithelial barrier. Faist A; Schloer S; Mecate-Zambrano A; Janowski J; Schreiber A; Boergeling Y; Conrad BCG; Kumar S; Toebben L; Schughart K; Baumgardt M; Kessler M; Hoenzke K; Hocke A; Trautmann M; Kato H; Hartmann W; Christersson A; Rescher U; Mellmann A; Kuehn J; Kuempers P; Wolff T; Wiewrodt R; Rovas A; Barth P; Wiebe K; Brunotte L; Ludwig S (2023) In: Antiviral Research, 209 Art der Publikation: Forschungsartikel (Zeitschrift)
The ubiquitination landscape of the influenza A virus polymerase Günl F.; Krischuns T.; Schreiber J.A.; Henschel L.; Wahrenburg M.; Drexler H.C.A.; Leidel S.A.; Cojocaru V.; Seebohm G.; Mellmann A.; Schwemmle M.; Ludwig S.; Brunotte L.; (2023) In: Nature Communications, 14(1) Art der Publikation: Forschungsartikel (Zeitschrift)
Cell-intrinsic genomic reassortment of pandemic H1N1 2009 and Eurasian avian-like swine influenza viruses results in potentially zoonotic variants. Ferrando VA; Friedrich ME; Gandhi S; Mellmann A; Masemann D; Christersson A; Anhlan D; Brunotte L; Stoll M; Harder T; Beer M; Boergeling Y; Ludwig S (2023) In: Emerging Microbes and Infections, 12(1) Art der Publikation: Forschungsartikel (Zeitschrift)
Glycolytic interference blocks influenza A virus propagation by impairing viral polymerase-driven synthesis of genomic vRNA. Kleinehr J; Schöfbänker M; Daniel K; Günl F; Mohamed FF; Janowski J; Brunotte L; Boergeling Y; Liebmann M; Behrens M; Gerdemann A; Klotz L; Esselen M; Humpf HU; Ludwig S; Hrincius ER (2023) In: PLoS Pathogens, 19(7) Art der Publikation: Forschungsartikel (Zeitschrift)
Surrogate Virus Neutralisation Test Based on Nanoluciferase-Tagged Antigens to Quantify Inhibitory Antibodies against SARS-CoV-2 and Characterise Omicron-Specific Reactivity in a… Schoefbaenker, M; Neddermeyer, R; Guenther, T; Mueller, MM; Romberg, ML; Classen, N; Hennies, MT; Hrincius, ER; Ludwig, S; Kuehn, JE; Lorentzen, EU (2023) In: Vaccines, 2023(11) Art der Publikation: Forschungsartikel (Zeitschrift)
Hypericum perforatum and Its Ingredients Hypericin and Pseudohypericin Demonstrate an Antiviral Activity against SARS-CoV-2. Mohamed, Fakry F.; Anhlan, Darisuren; Schöfbänker, Michael; Schreiber, André; Classen, Nica; Hensel, Andreas; Hempel, Georg; Scholz, Wolfgang; Kühn, Joachim; Hrincius, Eike R., Stephan Ludwig (2022) In: Pharmaceuticals, 15(5) Art der Publikation: Forschungsartikel (Zeitschrift)
Small spleen peptides prevent development of psoriatic arthritis via restoration of peripheral tolerance Wixler, V; Zaytsev, IZ; Leite Dantas, R; Schied, T; Boergeling, Y; Lührmann, V; Varga, G; Masemann, D; Ludwig, S (2022) In: Molecular Therapy, 30(2) Art der Publikation: Forschungsartikel (Zeitschrift)