PDCD4 controls the G1/S-phase transition in a telomerase-immortalized epithelial cell line and affects the expression level and translation of multiple mRNAs

Haas A, Nilges BS, Leidel SA, Klempnauer K-H (2020)
In: Scientific Reports, 2020
Art der Publikation: Forschungsartikel (Zeitschrift)

A novel cell-based screening assay for small-molecule MYB inhibitors identifies podophyllotoxins teniposide and etoposide as inhibitors of MYB activity.

Yusenko M, Jakobs A, Klempnauer KH (2018)
In: Scientific Reports, 8
Art der Publikation: Forschungsartikel (Zeitschrift)

Interplay with the Mre11-Rad50-Nbs1 complex and phosphorylation by GSK3β implicate human B-Myb in DNA-damage signaling

Henrich S., Usadel C., Werwein E., Burdova K., Janscak P., Ferrari S., Hess D., Klempnauer K. (2017)
In: Scientific Reports, 7(null)
Art der Publikation: Forschungsartikel (Zeitschrift)

Withaferin A, a natural compound with anti-tumor activity, is a potent inhibitor of transcription factor C/EBPβ

Falkenberg K., Jakobs A., Matern J., Dörner W., Uttarkar S., Trentmann A., Steinmann S., Coulibaly A., Schomburg C., Mootz H., Schmidt T., Klempnauer K. (2017)
In: Biochimica et Biophysica Acta - Molecular Cell Research, 1864(7)
Art der Publikation: Forschungsartikel (Zeitschrift)

Targeting acute myeloid leukemia with a small molecule inhibitor of the Myb/p300 interaction

Uttarkar S., Dassé E., Coulibaly A., Steinmann S., Jakobs A., Schomburg C., Trentmann A., Jose J., Schlenke P., Berdel W., Schmidt T., Müller-Tidow C., Frampton J., Klempnauer K. (2016)
In: Blood, 127(9)
Art der Publikation: Forschungsartikel (Zeitschrift)

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Natural Products with Antitumor Potential targeting the MYB-C/EBPbeta-p300 Transcription Module Schmidt TJ, Klempnauer K-H. (2022) In: Molecules, 27 Art der Publikation: Forschungsartikel (Zeitschrift)
PDCD4 controls the G1/S-phase transition in a telomerase-immortalized epithelial cell line and affects the expression level and translation of multiple mRNAs Haas A, Nilges BS, Leidel SA, Klempnauer K-H (2020) In: Scientific Reports, 2020 Art der Publikation: Forschungsartikel (Zeitschrift)
Activation of the oncogenic transcription factor B-Myb via multisite phosphorylation and prolyl cis/trans isomerization. Werwein E, Cibis H, Hess D, Klempnauer KH (2019) In: Nucleic Acids Research, 47 Art der Publikation: Forschungsartikel (Zeitschrift)
A novel cell-based screening assay for small-molecule MYB inhibitors identifies podophyllotoxins teniposide and etoposide as inhibitors of MYB activity. Yusenko M, Jakobs A, Klempnauer KH (2018) In: Scientific Reports, 8 Art der Publikation: Forschungsartikel (Zeitschrift)
1. The natural anti-tumor compound Celastrol targets a Myb-C/EBPβ-p300 transcriptional module implicated in myeloid gene expression. Coulibaly A, Haas A, Steinmann S, Jakobs A, Schmidt TJ, Klempnauer KH. (2018) In: PloS one, 13 Art der Publikation: Forschungsartikel (Zeitschrift)
Interplay with the Mre11-Rad50-Nbs1 complex and phosphorylation by GSK3β implicate human B-Myb in DNA-damage signaling Henrich S., Usadel C., Werwein E., Burdova K., Janscak P., Ferrari S., Hess D., Klempnauer K. (2017) In: Scientific Reports, 7(null) Art der Publikation: Forschungsartikel (Zeitschrift)
Targeting the transcription factor Myb by small-molecule inhibitors Uttarkar S., Frampton J., Klempnauer K. (2017) In: Experimental Hematology, 2017(47) Art der Publikation: Forschungsartikel (Zeitschrift)
Withaferin A, a natural compound with anti-tumor activity, is a potent inhibitor of transcription factor C/EBPβ Falkenberg K., Jakobs A., Matern J., Dörner W., Uttarkar S., Trentmann A., Steinmann S., Coulibaly A., Schomburg C., Mootz H., Schmidt T., Klempnauer K. (2017) In: Biochimica et Biophysica Acta - Molecular Cell Research, 1864(7) Art der Publikation: Forschungsartikel (Zeitschrift)
An isoform-specific C/EBPb inhibitor targets acute myeloid leukemia cells. Jakobs A, Uttarkar S, Schomburg C, Steinmann S, Coulibaly A, Schlenke P, Berdel W, Müller-Tidow C, Schmidt TJ, Klempnauer K-H. (2016) In: Leukemia, 30 Art der Publikation: Forschungsartikel (Zeitschrift)
Targeting acute myeloid leukemia with a small molecule inhibitor of the Myb/p300 interaction Uttarkar S., Dassé E., Coulibaly A., Steinmann S., Jakobs A., Schomburg C., Trentmann A., Jose J., Schlenke P., Berdel W., Schmidt T., Müller-Tidow C., Frampton J., Klempnauer K. (2016) In: Blood, 127(9) Art der Publikation: Forschungsartikel (Zeitschrift)