Oxadiazole-substituted naphtho[2,3-b]thiophene-4,9-diones as potent inhibitors of keratinocyte hyperproliferation. Structure−activity relationships of the tricyclic quinone skeleton and the oxadiazole substituent

Basoglu A, Dirkmann S, Zahedi Golpayegani N, Vortherms S, Tentrop J, Nowottnik D, Prinz H, Fröhlich R, Müller K (2017)

In: European Journal of Medicinal Chemistry, 134, 119-132. doi:10.1016/j.ejmech.2017.03.084

Forschungsartikel (Zeitschrift) | Peer reviewed | Veröffentlicht

8-Halo-substituted naphtho[2,3-b]thiophene-4,9-diones as redox-active inhibitors of keratinocyte hyperproliferation with reduced membrane-damaging properties

Lindenschmidt C, Krane D, Vortherms S, Hilbig L, Prinz H, Müller K (2016)

In: European Journal of Medicinal Chemistry, 110, 280-290. doi:10.1016/j.ejmech.2016.01.040

Forschungsartikel (Zeitschrift) | Peer reviewed | Veröffentlicht

Natural product derived antiprotozoal agents: Synthesis, biological evaluation, and structure-activity relationships of novel chromene and chromane derivatives

Harel D., Schepmann D., Prinz H., Brun R., Schmidt T.J., Wunsch B. (2013)

In: Journal of Medicinal Chemistry, 56(18), 7442-7448. doi:10.1021/jm401007p

Forschungsartikel (Zeitschrift) | Peer reviewed

Phenylimino-10H-anthracen-9-ones as novel antimicrotubule agents-synthesis, antiproliferative activity and inhibition of tubulin polymerization.

In: , -.

| Peer reviewed

Structure-activity relationship studies of acridones as potential antipsoriatic agents. 1. Synthesis and antiproliferative activity of simple N-unsubstituted 10H-acridin-9-ones against human keratinocyte growth

In: , -.

| Peer reviewed

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Oxadiazole-substituted naphtho[2,3-b]thiophene-4,9-diones as potent inhibitors of keratinocyte hyperproliferation. Structure−activity relationships of the tricyclic quinone skeleton and the oxadiazole substituent Basoglu A, Dirkmann S, Zahedi Golpayegani N, Vortherms S, Tentrop J, Nowottnik D, Prinz H, Fröhlich R, Müller K (2017) In: European Journal of Medicinal Chemistry, 134, 119-132. doi:10.1016/j.ejmech.2017.03.084 Forschungsartikel (Zeitschrift) \| Peer reviewed \| Veröffentlicht
N-Heterocyclic (4-phenylpiperazin-1-yl)methanones derived from phenoxazine and phenothiazine as highly potent inhibitors of tubulin polymerization Prinz H, Ridder A, Vogel K, Böhm KJ, Ivanov I, Ghasemi JB, Aghaee E, Müller K (2017) In: Journal of Medicinal Chemistry, 60(2), 749-766. doi:10.1021/acs.jmedchem.6b01591 Forschungsartikel (Zeitschrift) \| Peer reviewed \| Veröffentlicht
8-Halo-substituted naphtho[2,3-b]thiophene-4,9-diones as redox-active inhibitors of keratinocyte hyperproliferation with reduced membrane-damaging properties Lindenschmidt C, Krane D, Vortherms S, Hilbig L, Prinz H, Müller K (2016) In: European Journal of Medicinal Chemistry, 110, 280-290. doi:10.1016/j.ejmech.2016.01.040 Forschungsartikel (Zeitschrift) \| Peer reviewed \| Veröffentlicht
Inhibitory effect of phenothiazine- and phenoxazine-derived chloroacetamides on Leishmania major growth and Trypanosoma brucei trypanothione reductase Marcu A, Schurigt U, Müller K, Moll H, Krauth-Siegel RL, Prinz H (2016) In: European Journal of Medicinal Chemistry, 108, 436-443. doi:10.1016/j.ejmech.2015.11.023 Forschungsartikel (Zeitschrift) \| Peer reviewed \| Veröffentlicht
Natural product derived antiprotozoal agents: Synthesis, biological evaluation, and structure-activity relationships of novel chromene and chromane derivatives Harel D., Schepmann D., Prinz H., Brun R., Schmidt T.J., Wunsch B. (2013) In: Journal of Medicinal Chemistry, 56(18), 7442-7448. doi:10.1021/jm401007p Forschungsartikel (Zeitschrift) \| Peer reviewed
Synthesis and structure–sctivity relationships of lapacho analogues. 1. Suppression of human keratinocyte hyperproliferation by 2-substituted naphtho[2,3-b]furan-4,9-diones, activation by enzymatic one- and two-electron reduction, and intracellular generation of superoxide In: , -. \| Peer reviewed
Phenylimino-10H-anthracen-9-ones as novel antimicrotubule agents-synthesis, antiproliferative activity and inhibition of tubulin polymerization. In: , -. \| Peer reviewed
N-Benzoylated phenoxazines and phenothiazines: synthesis, antiproliferative activity, and inhibition of tubulin polymerization. In: , -. \| Peer reviewed
Structure-activity relationship studies of acridones as potential antipsoriatic agents. 1. Synthesis and antiproliferative activity of simple N-unsubstituted 10H-acridin-9-ones against human keratinocyte growth In: , -. \| Peer reviewed
Structure-activity relationship studies of acridones as potential antipsoriatic agents. 2. Synthesis and antiproliferative activity of 10-substituted hydroxy-10H-acridin-9-ones against human keratinocyte growth In: , -. \| Peer reviewed