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Zeige 1 bis 10 von 131 Ergebnissen

Restoration of Defective CFTR in Human Nasal Respiratory Epithelial Cells by CFTR Modulators and mRNA Transfection Singh, Roshani ,Narayan; Horn, Marilia, Marta; Juko, Marin; Kampshoff, Ami; Schmid, Jochen; Omran, Heymut; Zhang, Dandan; Rosenecker, Joseph; Weber, Wolf-Michael; Große-Onnebrink, Jörg, (2026) In: International Journal of Molecular Sciences, 27(4). doi:10.3390/ijms27042063 Forschungsartikel (Zeitschrift) \| Peer reviewed \| Veröffentlicht
Consensus molecular subtyping of colorectal carcinoma brain metastases reveals a metabolic signature associated with poor patient survival Irmer B; Wlochowitz D; Krekeler C; Richter KM; Chandrabalan S; Bayerlova M; Wolff A; Lenz G; Conradi LC; Schildhaus HU; Stadelmann C; Rohde V; Proescholdt M; Salinas G; Homayounfar K; Kuhlmann T; Hailfinger S; Pukrop T; Menck K; Beissbarth T; Bleckmann A (2025) In: Molecular Oncology, 2025(1). doi:10.1002/1878-0261.13748 Forschungsartikel (Zeitschrift) \| Peer reviewed \| Veröffentlicht
ETMR stem-like state and chemo-resistance are supported by perivascular cells at single-cell resolution de Faria, Flavia W.; Riedel, Nicole C.; Münter, Daniel; Interlandi, Marta; Göbel, Carolin; Altendorf, Lea; Richter, Mathis; Melcher, Viktoria; Thomas, Christian; Roy, Rajanya; Schoof, Melanie; Bedzhov, Ivan; Moreno, Natalia; Graf, Monika; Hotfilder, Marc; Holdhof, Dörthe; Hartmann, Wolfgang; Bruns, Ann-Katrin; Brentrup, Angela; Liesche-Starnecker, Friederike; Maerkl, Bruno; Sandmann, Sarah; Varghese, Julian; Dugas, Martin; Pinto, Pedro H.; Balbach, Sebastian T.;Lu, I-Na; Rossig, Claudia; Soehnlein, Oliver; Canak, Aysegül; Ebinger, Martin; Schuhmann, Martin; Schittenhelm, Jens; Frühwald, Michael F.; Schüller, Ulrich; Albert, Thomas K.; Walter, Carolin; Bruder, Jan M.; Kerl, Kornelius. (2025) In: Nature Communications, 16, 5394. doi:10.1038/s41467-025-60442-9 Forschungsartikel (Zeitschrift) \| Peer reviewed \| Veröffentlicht
Satb1 directs the differentiation of TH17 cells through suppression of IL-2 expression. Köhne M; Shakiba MH; Schmidleithner L; Schulte-Schrepping J; Scholz R; Elmzzahi T; Sommer D; Li Y; Carraro C; De Domenico E; Wißfeld J; Händler K; Hamada D; Frolov A; Cheng X; Baumgart AK; Holsten L; Osei-Sarpong C; Bourry S; Thabet Y; Renken H; Paulusch S; Sadlon T; Buch T; Wunderlich FT; Wickenhauser C; Alferink J; Kuhlmann T; Geyer M; Bonaguro L; Barry SC; Schultze JL; Beyer MD (2025) In: Cell Reports, 44(7), 115866-115866. doi:10.1016/j.celrep.2025.115866 Forschungsartikel (Zeitschrift) \| Peer reviewed \| Veröffentlicht
Cell-mediated cytotoxicity within CSF and brain parenchyma in spinal muscular atrophy unaltered by nusinersen treatment Lu, I; Heming, M; Cheung, P; Thomas, C; Dag, M; Giglio, G; Schroeter, C; Nelke, C; Wirth, T; König, S; Siveke, J; Klotz, L; Leo, M; Wiendl, H; Hagenacker, T; Meyer zu Hörste, G (2024) In: Nature Communications, 15, 4120. doi:10.1038/s41467-024-48195-3 Forschungsartikel (Zeitschrift) \| Peer reviewed \| Veröffentlicht
Enhanced pathogenicity of Th17 cells due to natalizumab treatment: Implications for MS disease rebound In: , -. \| Peer reviewed
Protoporphyrin IX (PpIX) Fluorescence during Meningioma Surgery: Correlations with Histological Findings and Expression of Heme Pathway Molecules In: , . \| Peer reviewed
MAPK inhibitor sensitivity scores predict sensitivity driven by the immune infiltration in pediatric low-grade gliomas In: . \| Peer reviewed
DRUG-CLASS SPECIFIC GENE-BASED MAPK SENSITIVITY SCORES (MSS) PREDICT SENSITIVITY TO MAPK INHIBITORS AND IDENTIFY IMMUNE INFILTRATION AS PUTATIVE TARGET IN PEDIATRIC LOW-GRADE GLIOMAS In: . \| Peer reviewed
Stroke induces disease-specific myeloid cells in the brain parenchyma and pia. In: , -. \| Peer reviewed

Janoschka C; Lindner M; Koppers N; Starost L; Liebmann M; Eschborn M; Schneider-Hohendorf T; Windener F; Schafflick D; Fleck AK; Koch K; Deffner M; Schwarze AS; Schulte-Mecklenbeck A; Metz I; Gross CC; Meuth SG; Schwab N; Meyer Zu Hörste G; Wiendl H; Kuhlmann T; Klotz L; Stoll M

(2023)

Proceedings of the National Academy of Sciences of the United States of America

, 120

(1)

e2209944120

doi:10.1073/pnas.2209944120

Forschungsartikel (Zeitschrift)

| Veröffentlicht

Spille, D.C.; Bunk, E.C.; Thomas, C.; Özdemir, Z.; Wagner, A.; Akkurt, B.H.; Mannil, M.; Paulus, W.; Grauer, O.M.; Stummer, W.; Senner, V.; Brokinkel, B.

(2023)

Cancers

, 15

(1)

304

doi:10.3390/cancers15010304

Forschungsartikel (Zeitschrift)

| Veröffentlicht

Sigaud R.; Albert T.K.; Hess C.; Hielscher T.; Winkler N.; Kocher D.; Walter C.; Münter D.; Selt F.; Usta D.; Ecker J.; Brentrup A.; Hasselblatt M.; Thomas C.; Varghese J.; Capper D.; Thomale U.W.; Hernáiz Driever P.; Simon M.; Horn S.; Herz N.A.; Koch A.; Sahm F.; Hamelmann S.; Faria-Andrade A.; Jabado N.; Schuhmann M.U.; Schouten-van Meeteren A.Y.N.; Hoving E.; Brummer T.; van Tilburg C.M.; Pfister S.M.; Witt O.; Jones D.T.W.; Kerl K.; Milde T.

(2023)

Nature Communications

, 14

(1)

doi:10.1038/s41467-023-40235-8

Forschungsartikel (Zeitschrift)

| Veröffentlicht

Sigaud, Romain; Albert, Thomas K.; Hess, Caroline; Hielscher, Thomas; Winkler, Nadine; Walter, Carolin; Muenter, Daniel; Selt, Florian; Usta, Diren; Ecker, Jonas; Brentrup, Angela; Hasselblatt, Martin; Thomas, Christian; Varghese, Julian; Capper, David; Thomale, Ulrich W.; Driever, Pablo Hernaiz; Simon, Michele; Horn, Svea; Herz, Nina Annika; Koch, Arend; Sahm, Felix; Mann, Stefan Hamel; Andrade, Augusto Faria; Jabado, Nada; Schouten-van Meeteren, Antoinette Y. N.; Hoving, Eelco; Brummer, Tilman; van Tilburg, Cornelis M.; Pfister, Stefan M.; Witt, Olaf; Jones, David T. W.; Kerl, Kornelius; Milde, Till

(2023)

Neuro-Oncology

, 25

doi:10.1093/neuonc/noad073.212

Forschungsartikel (Zeitschrift)

| Veröffentlicht

Beuker C, Schafflick D, Strecker JK, Heming M, Li X, Wolbert J, Schmidt-Pogoda A, Thomas C, Kuhlmann T, Aranda-Pardos I, A-Gonzalez N, Kumar PA, Werner Y, Kilic E, Hermann DM, Stumm R, Wiendl H, Minnerup J, Meyer Zu Hörste G

(2022)

Nature Communications

, 13

(1)

945

doi:10.1038/s41467-022-28593-1

Forschungsartikel (Zeitschrift)

| Veröffentlicht

Restoration of Defective CFTR in Human Nasal Respiratory Epithelial Cells by CFTR Modulators and mRNA Transfection Singh, Roshani ,Narayan; Horn, Marilia, Marta; Juko, Marin; Kampshoff, Ami; Schmid, Jochen; Omran, Heymut; Zhang, Dandan; Rosenecker, Joseph; Weber, Wolf-Michael; Große-Onnebrink, Jörg, (2026) In: International Journal of Molecular Sciences, 27(4). doi:10.3390/ijms27042063 Forschungsartikel (Zeitschrift) \| Peer reviewed \| Veröffentlicht
Consensus molecular subtyping of colorectal carcinoma brain metastases reveals a metabolic signature associated with poor patient survival Irmer B; Wlochowitz D; Krekeler C; Richter KM; Chandrabalan S; Bayerlova M; Wolff A; Lenz G; Conradi LC; Schildhaus HU; Stadelmann C; Rohde V; Proescholdt M; Salinas G; Homayounfar K; Kuhlmann T; Hailfinger S; Pukrop T; Menck K; Beissbarth T; Bleckmann A (2025) In: Molecular Oncology, 2025(1). doi:10.1002/1878-0261.13748 Forschungsartikel (Zeitschrift) \| Peer reviewed \| Veröffentlicht
ETMR stem-like state and chemo-resistance are supported by perivascular cells at single-cell resolution de Faria, Flavia W.; Riedel, Nicole C.; Münter, Daniel; Interlandi, Marta; Göbel, Carolin; Altendorf, Lea; Richter, Mathis; Melcher, Viktoria; Thomas, Christian; Roy, Rajanya; Schoof, Melanie; Bedzhov, Ivan; Moreno, Natalia; Graf, Monika; Hotfilder, Marc; Holdhof, Dörthe; Hartmann, Wolfgang; Bruns, Ann-Katrin; Brentrup, Angela; Liesche-Starnecker, Friederike; Maerkl, Bruno; Sandmann, Sarah; Varghese, Julian; Dugas, Martin; Pinto, Pedro H.; Balbach, Sebastian T.;Lu, I-Na; Rossig, Claudia; Soehnlein, Oliver; Canak, Aysegül; Ebinger, Martin; Schuhmann, Martin; Schittenhelm, Jens; Frühwald, Michael F.; Schüller, Ulrich; Albert, Thomas K.; Walter, Carolin; Bruder, Jan M.; Kerl, Kornelius. (2025) In: Nature Communications, 16, 5394. doi:10.1038/s41467-025-60442-9 Forschungsartikel (Zeitschrift) \| Peer reviewed \| Veröffentlicht
Satb1 directs the differentiation of TH17 cells through suppression of IL-2 expression. Köhne M; Shakiba MH; Schmidleithner L; Schulte-Schrepping J; Scholz R; Elmzzahi T; Sommer D; Li Y; Carraro C; De Domenico E; Wißfeld J; Händler K; Hamada D; Frolov A; Cheng X; Baumgart AK; Holsten L; Osei-Sarpong C; Bourry S; Thabet Y; Renken H; Paulusch S; Sadlon T; Buch T; Wunderlich FT; Wickenhauser C; Alferink J; Kuhlmann T; Geyer M; Bonaguro L; Barry SC; Schultze JL; Beyer MD (2025) In: Cell Reports, 44(7), 115866-115866. doi:10.1016/j.celrep.2025.115866 Forschungsartikel (Zeitschrift) \| Peer reviewed \| Veröffentlicht
Cell-mediated cytotoxicity within CSF and brain parenchyma in spinal muscular atrophy unaltered by nusinersen treatment Lu, I; Heming, M; Cheung, P; Thomas, C; Dag, M; Giglio, G; Schroeter, C; Nelke, C; Wirth, T; König, S; Siveke, J; Klotz, L; Leo, M; Wiendl, H; Hagenacker, T; Meyer zu Hörste, G (2024) In: Nature Communications, 15, 4120. doi:10.1038/s41467-024-48195-3 Forschungsartikel (Zeitschrift) \| Peer reviewed \| Veröffentlicht
Enhanced pathogenicity of Th17 cells due to natalizumab treatment: Implications for MS disease rebound In: , -. \| Peer reviewed
Protoporphyrin IX (PpIX) Fluorescence during Meningioma Surgery: Correlations with Histological Findings and Expression of Heme Pathway Molecules In: , . \| Peer reviewed
MAPK inhibitor sensitivity scores predict sensitivity driven by the immune infiltration in pediatric low-grade gliomas In: . \| Peer reviewed
DRUG-CLASS SPECIFIC GENE-BASED MAPK SENSITIVITY SCORES (MSS) PREDICT SENSITIVITY TO MAPK INHIBITORS AND IDENTIFY IMMUNE INFILTRATION AS PUTATIVE TARGET IN PEDIATRIC LOW-GRADE GLIOMAS In: . \| Peer reviewed
Stroke induces disease-specific myeloid cells in the brain parenchyma and pia. In: , -. \| Peer reviewed